KITALYSIS-CUCN

KitAlysis^™ High-Throughput Copper C-N Cross-Coupling Reaction Screening Kit-Pack of 2

• Synonym(s): Copper Catalyzed C-N Coupling Kit
• UNSPSC Code: 12161503
• NACRES: NA.22

Properties

• reaction suitability: core: palladium; reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: catalyst; reaction type: Cross Couplings

Description

Application

Screening kit for Copper C-N Cross-Coupling Reactions. Step-by-step user guides and a downloadable experimental excel sheets are provided in the below hyperlinks.

Step-by-Step Guide for KitAlysis^™ High-Throughput Copper C-N Cross-Coupling Reaction Screening Kit

Downloadable experimental excel sheet

Each kit contains 2 customizable screening sets that include the following components:

• 24 (6 x 4) pre-weighed ligands in glass vials loaded with stir bars, topped with cap mat
• Potassium phosphate: 4 pre-weighed vials with product labels and lids
• CuI (soluble source) in preweighed vial
• 4 degassed anhydrous solvents (dioxane, DMAc, toluene, and DMSO) in ampules
• 1 internal standard
• 2 KitAlysis 24-Well reaction block replacement films
• 8 stir bars for stock solutions
• Ampule cracker

Monitor reaction progress via TLC-MS by following this protocol

Best when used with KitAlysis Benchtop Inertion Box and 24-well Reaction Block (sold separately).

Features and Benefits

• Designed and tested by synthetic chemists.
• Easily run 24-microscale reaction in parallel.
• Suggested conditions: 10 μmol reactions with 1 μmol catalyst (10 mol%) 0.1 M concentration, and 3 equiv. base.
• Customizable and downloadable Excel Template for quick calculations and easy incorporation into electronic laboratory notebooks.

Legal Information

KitAlysis is a trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS02,GHS08,GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H225,H302 + H312 + H332,H304,H315,H318,H335,H336,H350,H360D,H373,H410
• Precautionary Statements: P210 - P273 - P280 - P301 + P310 - P305 + P351 + P338 - P331
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Asp. Tox. 1 - Carc. 1B - Eye Dam. 1 - Flam. Liq. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 2 Inhalation - STOT SE 3
• Target Organs: Central nervous system, Respiratory system
• Supplementary Hazards: EUH019
• Storage Class Code: 3 - Flammable liquids
• Flash Point(F): 39.2 °F
• Flash Point(C): 4 °C