Skip to Content
Merck
All Photos(1)

Key Documents

More Documents

652369

Sigma-Aldrich

1-Amino-1-cyclobutanecarboxylic acid

97%

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
H2NC4H6CO2H
CAS Number:
22264-50-2
Molecular Weight:
115.13
MDL number:
MFCD00661068
UNSPSC Code:
12352106
PubChem Substance ID:
24883877
NACRES:
NA.22

Quality Level

100

Assay

97%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

261 °C (dec.) (lit.)

application(s)

peptide synthesis

SMILES string

NC1(CCC1)C(O)=O

InChI

1S/C5H9NO2/c6-5(4(7)8)2-1-3-5/h1-3,6H2,(H,7,8)

InChI key

FVTVMQPGKVHSEY-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302 - H315 - H319 - H335

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Y Gaoni et al.
Journal of medicinal chemistry, 37(25), 4288-4296 (1994-12-09)
A range of cis- and trans-3-substituted 1-aminocyclobutane-1-carboxylic acids has been synthesized and evaluated for antagonism at excitatory amino acid receptor sites and for anticonvulsant activity. Potent and selective antagonist activity at N-methyl-D-aspartate (NMDA) receptor sites in neonatal rat motoneurones was
V N Balaji et al.
Peptide research, 8(3), 178-186 (1995-05-01)
Conformationally constrained peptidomimetics are being increasingly used in the development of 3-D pharmacophores of peptide-based drug candidates and to alter their metabolic stability towards achievements of oral bioavailability. Here we present conformational energy calculations on model compounds containing 1-aminocyclobutane carboxylic
T S Rao et al.
Neuropharmacology, 29(3), 305-309 (1990-03-01)
Following intravenous administration, 1-aminocyclobutane-1-carboxylate (ACBC, 100 mg/kg), a N-methyl-D-aspartate (NMDA)-associated glycine receptor antagonist, was eliminated with a T1/2 of 5 min in mouse brain and 4 min in rat cerebrospinal fluid (CSF). 1-Aminocyclopropane-1-carboxylate (ACC), a NMDA-associated glycine receptor agonist, was
R P Compton et al.
European journal of pharmacology, 188(1), 63-70 (1990-01-23)
Activation of the N-methyl-D-aspartate (NMDA) receptor complex is subject to modulation via interactions at a coupled [3H]glycine recognition site in rat brain synaptic plasma membranes (SPM). We examined the effect of the potent and specific glycine site antagonists, 1-hydroxy-3-amino-2-pyrrolidone (HA-966)
L C Washburn et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 20(10), 1055-1061 (1979-10-01)
1-Aminocyclobutane[14C]carboxylic acid [C-14) ACBC] was incorporated preferentially by several tumor types in rats and hamsters. The agent was cleared rapidly from rat blood, attaining its maximum tissue concentrations within 30 min after i.v. injection. Carrier ACBC had little effect on
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service