592021
Nicotinamide-(amide-15N)
98 atom % 15N, 98% (CP)
Synonym(s):
3-Pyridine(carboxamide-15N), Vitamin B3-(amide-15N)
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About This Item
Empirical Formula (Hill Notation):
C6H615NNO
CAS Number:
Molecular Weight:
123.12
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
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isotopic purity
98 atom % 15N
Quality Level
Assay
98% (CP)
form
solid
technique(s)
mass spectrometry (MS): suitable
color
white
mp
130-132 °C (lit.)
mass shift
M+1
SMILES string
[15NH2]C(=O)c1cccnc1
InChI
1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)/i7+1
InChI key
DFPAKSUCGFBDDF-CDYZYAPPSA-N
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General description
Nicotinamide (or niacinamide) is an amide form of vitamin B3/nicotinic acid that can be used in a variety of cosmetic and pharmaceutical applications. It is found in meat, fish, nuts, and mushrooms, as well as in some vegetables. It is also a precursor for essential coenzymes.
Application
Nicotinamide-(amide-15N) can be utilized in the biosynthesis of nicotinamide adenine dinucleotide (NAD). This product can also be used as an analytical standard.
Packaging
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Certificates of Analysis (COA)
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Safety of high-dose nicotinamide: a review
Knip M, et al.
Diabetologia, 43(11), 1337-1345 (2000)
A review of nicotinamide: treatment of skin diseases and potential side effects
Rolfe HM
Journal of Cosmetic Dermatology, 13(4), 324-328 (2014)
Igor Shats et al.
Cell metabolism, 31(3), 564-579 (2020-03-05)
Nicotinamide adenine dinucleotide (NAD), a cofactor for hundreds of metabolic reactions in all cell types, plays an essential role in metabolism, DNA repair, and aging. However, how NAD metabolism is impacted by the environment remains unclear. Here, we report an
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme.
Rong Grace Zhai et al.
Cellular and molecular life sciences : CMLS, 66(17), 2805-2818 (2009-05-19)
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase (NMNAT) has long been known as the master enzyme in NAD biosynthesis in living organisms. A burst of investigations on NMNAT, going beyond enzymology, have paralleled increasing discoveries of key roles played by NAD homeostasis in
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