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Key Documents

236365

Sigma-Aldrich

Sebacoyl chloride

99%

Synonym(s):

Sebacyl chloride

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About This Item

Linear Formula:
ClCO(CH2)8COCl
CAS Number:
Molecular Weight:
239.14
Beilstein:
1365665
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

Quality Level

Assay

99%

form

liquid

refractive index

n20/D 1.468 (lit.)

bp

168 °C/12 mmHg (lit.)

mp

−5-−3 °C (lit.)

density

1.121 g/mL at 25 °C (lit.)

SMILES string

ClC(=O)CCCCCCCCC(Cl)=O

InChI

1S/C10H16Cl2O2/c11-9(13)7-5-3-1-2-4-6-8-10(12)14/h1-8H2

InChI key

WMPOZLHMGVKUEJ-UHFFFAOYSA-N

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Application

Sebacocyl chloride (SC) can be used as a lipophilic monomer for the formation of polyamide microcapsules by an interfacial polycondensation reaction. It can also be utilized in the synthesis of modified chitosan nanoparticle hydrogels with high absorption capacity and high swelling ratio for the removal of metal ions from an aqueous solution. SC can also be used in the preparation of sebacic biscyclocarbonate, which can be used in the synthesis of biobased nonisocyanate polyurethanes.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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P L Madan et al.
Pharmaceutical research, 6(8), 714-718 (1989-08-01)
The effect of selected variables on the release characteristics of theophylline microcapsules prepared with 1,6-hexamethylene diamine and sebacoyl chloride via interfacial polycondensation has been investigated. The nature of the microcapsules and the release characteristics of theophylline from the microcapsules were
Marianna Sikorska et al.
BioFactors (Oxford, England), 18(1-4), 173-183 (2003-12-30)
We have derivatised alpha-tocopherol (vitamin E) to a water-soluble polyoxyethanyl-alpha - tocopheryl sebacate (PTS) and discovered that it formed a non-covalent complex with CoQ10 at a molar ratio of 2:1 (PTS-CoQ10). This complex was water-soluble and remained stable for extended
I Montasser et al.
International journal of pharmaceutics, 335(1-2), 176-179 (2006-12-19)
Formulation of nanocapsules based on polyureas and polyamides have been tested using a patented process. This method based on polycondensation reaction of two complementary monomers and spontaneous formation of oil in water emulsion, is an alternative concept to the known
Zhenhua Xu et al.
International journal of pharmaceutics, 426(1-2), 182-192 (2012-01-24)
In this study we describe a novel polymer, mPPS-FA, synthesized as a potential gene transfer vector. To complete mPPS-FA, folic acid was conjugated to a backbone (named mPPS) consisting of a copolymer of methyl PEG-2000, PEI-600, and sebacoyl chloride. (1)H
D Poncelet et al.
Journal of microencapsulation, 11(1), 31-40 (1994-01-01)
A microencapsulation technique is proposed involving the formation of a polyethyleneimine (PEI) membrane crosslinked by an acid dichloride. The membranes were formed at pH 8 in a non-polar solvent, conditions which are better suited for the encapsulation of biocatalysts or

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