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Key Documents

185086

Sigma-Aldrich

Sodium cyanate

96%

Synonym(s):

Sodium isocyanate, Zassol

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About This Item

Linear Formula:
NaOCN
CAS Number:
Molecular Weight:
65.01
Beilstein:
3655041
EC Number:
MDL number:
UNSPSC Code:
12161600
eCl@ss:
38060512
PubChem Substance ID:
NACRES:
NA.22

Assay

96%

reaction suitability

core: sodium
reagent type: catalyst

SMILES string

[Na+].[O-]C#N

InChI

1S/CHNO.Na/c2-1-3;/h3H;/q;+1/p-1

InChI key

ZVCDLGYNFYZZOK-UHFFFAOYSA-M

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Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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J Tor-Agbidye et al.
Brain research, 820(1-2), 12-19 (1999-02-19)
Sodium cyanate, a neurotoxic chemical in rodents, primates and humans, is implicated in neurodegenerative disorders in protein-deficient populations subsisting in parts of Africa on the cyanogenic plant cassava. The molecular and cellular mechanisms of cyanate neurotoxicity are not understood. This
K K Henderson et al.
Journal of applied physiology (Bethesda, Md. : 1985), 89(1), 265-272 (2000-07-25)
These studies were conducted to compare the effects on systemic O(2) transport of chronically vs. acutely increased Hb O(2) affinity. O(2) transport during maximal normoxic and hypoxic [inspired PO(2) (PI(O(2))) = 70 and 55 Torr, respectively] exercise was studied in
W McCanse et al.
Journal of applied physiology (Bethesda, Md. : 1985), 86(4), 1257-1263 (1999-04-08)
Systemic O2 transport during maximal exercise at different inspired PO2 (PIO2) values was studied in sodium cyanate-treated (CY) and nontreated (NT) rats. CY rats exhibited increased O2 affinity of Hb (exercise O2 half-saturation pressure of Hb = 27.5 vs. 42.5
Ekaterina V Vinogradova et al.
Journal of the American Chemical Society, 134(27), 11132-11135 (2012-06-22)
An efficient method for palladium-catalyzed cross-coupling of aryl chlorides and triflates with sodium cyanate is reported. The protocol allows for the synthesis of unsymmetrical N,N'-di- and N,N,N'-trisubstituted ureas in one pot and is tolerant of a wide range of functional
M Rivera-Ch et al.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 164(8), 659-662 (1995-01-01)
The Hb-O2 affinity and the erythropoietic response as a function of time were studied in mice treated with sodium cyanate for up to 2 months. Cyanate increased the Hb-O2 affinity in normoxic mice more than in chronically hypoxic mice. The

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