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182028

Sigma-Aldrich

Poly(ethylene oxide)

average MV 600,000 (nominal), powder, hydroxyl, BHT as inhibitor

Synonym(s):

Polyethylene oxide, PEO

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About This Item

Linear Formula:
(-CH2CH2O-)n
CAS Number:
25322-68-3
MDL number:
MFCD00081839
UNSPSC Code:
12352104
PubChem Substance ID:
24850972
NACRES:
NA.23

product name

Poly(ethylene oxide), average Mv 600,000 (nominal), powder

form

powder

Quality Level

100

mol wt

average Mv 600,000 (nominal)

contains

200-500 ppm BHT as inhibitor

viscosity

4,500-8,800 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

transition temp

Tm 65 °C

Ω-end

hydroxyl

α-end

hydroxyl

application(s)

battery manufacturing

SMILES string

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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General description

Poly(ethylene oxide)(PEO) is a high molecular weight, non-ionic water-soluble polymer. It forms agel on hydration and shows good swelling capacity. PEO polymers are non-toxicand widely used in drug delivery systems to enhance drug solubility.

Application

Poly(ethylene oxide) can be used to prepare:
  • Bioabsorbable and injectable hydrogels for sustained drug release.
  • PEO/graphene oxide composite electrolyte membrane for fuel cells.
  • Poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. Losartan potassium encapsulated (PEO-b-PCL) copolymer can be used as a drug carrier.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ8481
MKCQ5773
MKCQ5772
MKCQ1413
MKCQ1412

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D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in
M Patel Geeta et al.
Current drug delivery, 6(2), 159-165 (2009-05-20)
Carbamazepine indicated for the control of epilepsy, undergoes extensive hepatic first-pass metabolism after oral administration. A vaginal dosage form of carbamazepine is not commercially available. Conventional suppository having poor retention in the vaginal tract, as they are removed in a
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced

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