103543

4-Nitroanisole

97%

• Synonym(s): 1-Methoxy-4-nitrobenzene
• Linear Formula: O₂NC₆H₄OCH₃
• CAS Number: 100-17-4
• Molecular Weight: 153.14
• Beilstein: 1865361
• EC Number: 202-825-3
• MDL number: MFCD00007327
• UNSPSC Code: 12352100
• eCl@ss: 39032065
• PubChem Substance ID: 24846610
• NACRES: NA.22

Properties

• Assay: 97%
• form: solid
• density: 1.233 g/mL at 25 °C (lit.)
• SMILES string: COc1ccc(cc1)[N+]([O-])=O
• InChI: 1S/C7H7NO3/c1-11-7-4-2-6(3-5-7)8(9)10/h2-5H,1H3
• InChI key: BNUHAJGCKIQFGE-UHFFFAOYSA-N

Description

General description

4-Nitroanisole undergoes photochemical nucleophilic aromatic substitution by hydroxide ion to form 4-methoxyphenol and 4-nitrophenol.

Application

4-Nitroanisole was used as probe to determine Π^* of Kamlet-Taft solvent parameters and high pressure and supercritical water in the temperature range of 16-420 °C. 4-Nitroanisole was used as carbon and energy supplement for the isolation of Rhodococcus strains.

Biochem/physiol Actions

4-Nitroanisole is O-demethylated to 4-nitrophenol by human liver microsomes.

Safety Information

• Pictograms: GHS08
• Signal Word: Warning
• Hazard Statements: H351,H412
• Precautionary Statements: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Aquatic Chronic 3 - Carc. 2
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 1
• Flash Point(F): 266.0 °F - closed cup
• Flash Point(C): 130 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves