SUR1-TRPM4 and AQP4 form a heteromultimeric complex that amplifies ion/water osmotic coupling and drives astrocyte swelling.

SUR1-TRPM4 and AQP4 form a heteromultimeric complex that amplifies ion/water osmotic coupling and drives astrocyte swelling.

Glia (2017-09-15)

Jesse A Stokum, Min S Kwon, Seung K Woo, Orest Tsymbalyuk, Rudi Vennekens, Volodymyr Gerzanich, J Marc Simard

摘要

Astrocyte swelling occurs after central nervous system injury and contributes to brain swelling, which can increase mortality. Mechanisms proffered to explain astrocyte swelling emphasize the importance of either aquaporin-4 (AQP4), an astrocyte water channel, or of Na

材料

货号

品牌

产品描述

G5500

Sigma-Aldrich

L - (−) -葡萄糖, ≥99%

C9205

Sigma-Aldrich

抗-胶质纤维酸性蛋白(GFAP)−Cy3^™抗体，小鼠单克隆, clone G-A-5, purified from hybridoma cell culture

AB3594

Sigma-Aldrich

抗水通道蛋白4抗体，CT, Chemicon^®, from rabbit

SAB5201116

Sigma-Aldrich

Monoclonal Anti-Gfap - Fitc antibody produced in mouse, clone S206A-8, purified immunoglobulin