- Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release.
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release.
Proceedings of the National Academy of Sciences of the United States of America (2017-03-08)
Chuchu Zhang, Katalin F Medzihradszky, Elda E Sánchez, Allan I Basbaum, David Julius
PMID28265084
摘要
Pain-producing animal venoms contain evolutionarily honed toxins that can be exploited to study and manipulate somatosensory and nociceptive signaling pathways. From a functional screen, we have identified a secreted phospholipase A2 (sPLA2)-like protein, BomoTx, from the Brazilian lancehead pit viper (
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蛋白酶 来源于灰色链霉菌, powder, BioReagent, suitable for mouse embryo cell culture, ≥3.5 units/mg solid
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ProteoMass ™ 细胞色素 c MALDI-MS 标准品, vial of 10 nmol, (M+H+) 12,361.96 Da by calculation
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ProteoMass ™ ACTH 片段 18-39 MALDI-MS 标准品, vial of 10 nmol, monoisotopic mol wt 2,464.1989 Da