- Copper(II) acetate-catalyzed addition of arylboronic acids to aromatic aldehydes.
Copper(II) acetate-catalyzed addition of arylboronic acids to aromatic aldehydes.
The Journal of organic chemistry (2008-12-11)
Hanmei Zheng, Qiang Zhang, Jiuxi Chen, Miaochang Liu, Shuanghua Cheng, Jinchang Ding, Huayue Wu, Weike Su
PMID19067580
摘要
A novel copper-catalyzed protocol for the synthesis of carbinol derivatives has been developed. In the presence of copper(II) acetate and dppf, carbinol derivatives were prepared by the addition of arylboronic acids to aromatic aldehydes in good to excellent yields. Moreover, the rigorous exclusion of air or moisture is not required in these transformations.