跳转至内容
Merck
  • An expeditious synthesis of 4-hydroxy-2E-nonenal (4-HNE), its dimethyl acetal and of related compounds.

An expeditious synthesis of 4-hydroxy-2E-nonenal (4-HNE), its dimethyl acetal and of related compounds.

Chemistry and physics of lipids (2007-10-05)
Laurent Soulère, Yves Queneau, Alain Doutheau
摘要

The facile one step synthesis of 4-hydroxy-2E-nonenal and its dimethyl acetal via a cross-metathesis reaction between commercially available octen-3-ol and acrolein or its dimethyl acetal is reported. The method was extended to the synthesis of C6 and C12 4-hydroxy-2E-enals, their dimethyl acetal and of the 4-hydroxy-2E-nonenoic acid (4-HNA).

材料
货号
品牌
产品描述

Sigma-Aldrich
乙醛缩二甲醇, 95%
Sigma-Aldrich
1,1-二甲氧基乙烷, ≥97%, FG
Sigma-Aldrich
丙烯醛二甲缩醛, 98%