- Lipase catalyzed synthesis of benzyl acetate in solvent-free medium using vinyl acetate as acyl donor.
Lipase catalyzed synthesis of benzyl acetate in solvent-free medium using vinyl acetate as acyl donor.
Bioorganic & medicinal chemistry letters (2006-05-23)
Abir B Majumder, Bhupender Singh, Debjit Dutta, Sushabhan Sadhukhan, Munishwar N Gupta
PMID16714111
摘要
Use of vinyl acetate as acyl donor in transesterification of benzyl alcohol catalyzed by a commercially available lipase (Lipozyme RM IM) gave 100% conversion in 10 min. The excess acyl donor and the enzyme could be recovered and reused. Unlike the chemical catalytic processes, it produced no undesirable side product.