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Merck

P0102

Sigma-Aldrich

PKCβII Peptide Inhibitor I 三氟乙酸盐

≥95% (HPLC), lyophilized powder

别名:

Protein Kinase C Beta II Peptide Inhibitor I 三氟乙酸盐

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About This Item

经验公式(希尔记法):
C61H94N12O19 · xC2HF3O2
分子量:
1299.47 (free base basis)
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77

品質等級

化驗

≥95% (HPLC)

形狀

lyophilized powder

顏色

white

溶解度

H2O: >1 mg/mL

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

OC(=O)C(F)(F)F.CCCCCCCCCCCCCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(O)=O

InChI

1S/C61H94N12O19.C2HF3O2/c1-5-6-7-8-9-10-11-12-13-14-15-22-49(78)65-45(33-74)58(88)68-41(28-34(2)3)55(85)71-44(31-48(63)77)60(90)73-27-18-21-46(73)59(89)67-39(23-25-50(79)80)53(83)69-42(29-36-32-64-38-20-17-16-19-37(36)38)56(86)70-43(30-47(62)76)57(87)66-40(24-26-51(81)82)54(84)72-52(35(4)75)61(91)92;3-2(4,5)1(6)7/h16-17,19-20,32,34-35,39-46,52,64,74-75H,5-15,18,21-31,33H2,1-4H3,(H2,62,76)(H2,63,77)(H,65,78)(H,66,87)(H,67,89)(H,68,88)(H,69,83)(H,70,86)(H,71,85)(H,72,84)(H,79,80)(H,81,82)(H,91,92);(H,6,7)/t35-,39+,40+,41+,42+,43+,44+,45+,46+,52+;/m1./s1

InChI 密鑰

FATKAQBIAPMYQT-YPNBOXGNSA-N

Amino Acid Sequence

Myr-Ser-Leu-Asn-Pro-Glu-Trp-Asn-Glu-Thr

生化/生理作用

PKCβII Peptide Inhibitor I is a cell-permeable protein kinase C inhibitor.

特點和優勢

This compound is featured on the PKC page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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访问文档库

Didi Omiyi et al.
The Journal of pharmacology and experimental therapeutics, 314(2), 542-551 (2005-05-10)
Ischemia followed by reperfusion (I/R) in the presence of polymorphonuclear leukocytes (PMNs) results in a marked cardiac contractile dysfunction. A cell-permeable protein kinase C (PKC) betaII peptide inhibitor was used to test the hypothesis that PKC betaII inhibition could attenuate

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