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Merck

G0541

Sigma-Aldrich

Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert N1) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

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About This Item

MDL號碼:
分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

lyophilized powder

分子量

antigen 100 kDa

物種活性

rat

包裝

antibody small pack of 25 μg

技術

dot blot: 1:1000
immunohistochemistry: 1:1000
western blot: 1:1000

UniProt登錄號

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

免疫原

synthetic peptide representing the sequence of the N1 splice variant.

應用

Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert N1) antibody is suitable for dot blot, immunohistochemistry and western blot at a dilution of 1:1000.

生化/生理作用

NMDA receptors (NMDAR) are glutamate-gated ion channels. It is sensitive to N-methyl-D-aspartate (NMDA) and consists of several homologous subunits (NMDAR1). NMDAR is highly expressed in the central nervous system and involved in excitatory synaptic transmission as well as synaptic plasticity. The activity of NMDA receptors are modulated by glycine. It exhibits high calcium permeability and unique voltage-dependent sensitivity to magnesium. It has been reported that phosphorylated NMDA receptors may regulate their function and play a role in many forms of synaptic plasticity such as long-term potentiation.

外觀

Lyophilized powder from 5 mM ammonium bicarbonate (some residual salt may be present)

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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