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一般說明
Anti-cytokine antibodies occur frequently and are present in healthy individuals and patients with acquired immunodeficiency and autoimmune diseases. Cytokines offering protection against microbes can be targeted by cytokine autoantibodies, leading to life-threatening infections. Some infections associated with anti-cytokine antibodies include M. tuberculosis, Salmonella, S. aureus. E. coli, Histoplasma, and more. The presence of cytokine autoantibodies in autoimmune disease can influence disease severity and activity. These autoimmune diseases may include systemic lupus erythematosus, multiple sclerosis, Sjögren’s syndrome, rheumatoid arthritis, and acute respiratory distress syndrome. Measuring cytokine autoantibodies may be useful for disease monitoring and efficacy of treatment.The MILLIPLEX® Human Cytokine Autoantibody Expanded IgG Magnetic Bead Panel is a 23-plex kit to be used for the simultaneous detection of any or all of the listed analytes in serum and plasma samples.
應用
The MILLIPLEX® Human Cytokine Autoantibody Expanded IgG Panel is a bead-based qualitative assay based on the Luminex® xMAP® technology, which enables the simultaneous analysis of cytokine autoantibodies in human serum and plasma samples.
Analytes available:
Anti-BAFF, Anti-G-CSF, Anti-IFNβ, Anti-IFNγ, Anti-IL-1α, Anti-IL-6, Anti IL 8, Anti-IL-10, Anti-IL-12p40, Anti-IL-15, Anti-IL-17A, Anti-IL-17F, Anti-IL-18, Anti-IL-22, Anti-TNFα, Anti-IFNα2, Anti-GM-CSF, Anti-IL-2, Anti-IL-3, Anti-IL-4, Anti-Osteopontin, Anti-PF4, and Anti-IFNω
Panel Type: MAGNETIC Immune Response
Cross Reactivity: There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
Research Category: Inflammation & ImmunologyResearch Sub-Category: Inflammation & Autoimmune Mechanisms;Inflammation
Analytes available:
Anti-BAFF, Anti-G-CSF, Anti-IFNβ, Anti-IFNγ, Anti-IL-1α, Anti-IL-6, Anti IL 8, Anti-IL-10, Anti-IL-12p40, Anti-IL-15, Anti-IL-17A, Anti-IL-17F, Anti-IL-18, Anti-IL-22, Anti-TNFα, Anti-IFNα2, Anti-GM-CSF, Anti-IL-2, Anti-IL-3, Anti-IL-4, Anti-Osteopontin, Anti-PF4, and Anti-IFNω
Panel Type: MAGNETIC Immune Response
Cross Reactivity: There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes in this panel.
Research Category: Inflammation & ImmunologyResearch Sub-Category: Inflammation & Autoimmune Mechanisms;Inflammation
特點和優勢
Design your multiplex kit by choosing available analytes within this panel.
法律資訊
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
訊號詞
Warning
危險聲明
危險分類
Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
儲存類別代碼
10 - Combustible liquids
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