M-021

DL-美沙酮-d₃ 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 别名: DL-6-二甲氨基-4,4-二苯基-3-庚酮-1,1,1-d₃ 溶液, DL-美沙酮-(庚基-1,1,1-d₃) 溶液
• 经验公式（希尔记法）: C₂₁D₃H₂₄NO
• CAS号: 60263-63-0
• 分子量: 312.46
• EC號碼: 200-659-6
• MDL號碼: MFCD00673285
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329817743
• NACRES: NA.24

属性

• 等級: certified reference material
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 1.0 mg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology
• 格式: single component solution
• 質量偏移: M+3
• 儲存溫度: 2-8°C
• SMILES 字串: [2H]C([2H])([2H])CC(=O)C(CC(C)N(C)C)(c1ccccc1)c2ccccc2
• InChI: 1S/C21H27NO/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19/h6-15,17H,5,16H2,1-4H3/i1D3
• InChI 密鑰: USSIQXCVUWKGNF-FIBGUPNXSA-N

说明

一般說明

A stable-labeled internal standard applicable for use in isotope dilution methods or quantitation of methadone levels by GC/MS or LC/MS in forensic analysis, urine drug testing, pain prescription monitoring or clinical toxicology applications. Methadone is a synthetic opioid used medically as an analgesic and as a maintenance anti-addictive for use in patients with opioid dependency. The drug is sold under several trade names such as Symoron, Dolophine^®, Amidone, Methadose^®, Physeptone, or Heptadon.

應用

• Opioid pharmacokinetics research: (±)-Methadone-D3 solution is utilized in opioid pharmacokinetics research to track and analyze the metabolism of methadone, providing insights into its pharmacological properties and interaction dynamics (Beck et al., 2010).


• MethaDonemetabolism study: As a deuterated methaDonesolution, it is critical for detailed studies on drug metabolism, aiding in the understanding of methadone′s biotransformation and its implications for therapeutic efficacy and safety (Anggård et al., 1979).


• Mass spectrometry internal standard: Methadone-D3 serves as an internal standard in mass spectrometry, enhancing the precision of quantitative analyses in forensic and clinical toxicology (Johansen and Jensen, 2004).


• Analytical research: Employed in analytical research, Methadone-D3 solution facilitates the development of advanced analytical methods for the detection and quantification of opioids in various biological matrices (Lucas et al., 2000).


• Drug metabolism research: This solution is key in drug metabolism research, helping to identify the metabolic pathways and excretion profiles of methadone, which is crucial for developing effective dosing regimens and understanding drug interactions (Kintz et al., 1998).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Dolophine is a registered trademark of Roxane Laboratories, Inc.

Methadose is a registered trademark of Mallinckrodt Inc.

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup