XIAP
X-linked inhibitor of apoptosis
别名:
API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3
物种:
Human XIAP (331), Mouse Xiap (11798), Rat Xiap (63879), Zebrafish xiap (373108), domestic cat XIAP (101090594), Horse XIAP (100060870), dog XIAP (442989), chicken XIAP (395280), domestic guinea pig Xiap (100715778), naked mole-rat Xiap (101715865) ...展开
UniProtKB ID:
基因ID:
- Human(331) Summary: This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]
- Mouse(11798) X-linked inhibitor of apoptosis
- Rat(63879) X-linked inhibitor of apoptosis
- Zebrafish(373108) X-linked inhibitor of apoptosis
- domestic cat(101090594) X-linked inhibitor of apoptosis
- Horse(100060870) X-linked inhibitor of apoptosis
- dog(442989) X-linked inhibitor of apoptosis
- chicken(395280) X-linked inhibitor of apoptosis
- domestic guinea pig(100715778) X-linked inhibitor of apoptosis
- naked mole-rat(101715865) X-linked inhibitor of apoptosis
- Domestic Rabbit(100328700) X-linked inhibitor of apoptosis
- cow(281647) X-linked inhibitor of apoptosis
- sheep(101116381) X-linked inhibitor of apoptosis
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ELISA
Small Molecule - Antagonist
货号
说明
物种
Antibodies
货号
说明
物种反应性
应用
Anti-XIAP antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-XIAP Antibody, clone 3H4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, monkey, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-BIRC4 antibody produced in mouse, clone 1F4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-phospho-XIAP (pSer87) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot
[KO Validated]Anti-XIAP Antibody, clone 5S5Q7, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
immunoprecipitation (IP)
western blot
western blot