TOP1
topoisomerase (DNA) I
别名:
TOPI
物种:
Human TOP1 (7150), Mouse Top1 (21969), Rat Top1 (64550), fruit fly Top1 (32458), domestic cat TOP1 (101093174), dog TOP1 (477229), chicken TOP1 (396004), Zebrafish top1 (327179), domestic guinea pig Top1 (100716716), naked mole-rat Top1 (101704241) ...展开
UniProtKB ID:
基因ID:
- Human(7150) Summary: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]
- Mouse(21969) topoisomerase (DNA) I
- Rat(64550) topoisomerase (DNA) I
- fruit fly(32458) Topoisomerase 1
- domestic cat(101093174) topoisomerase (DNA) I
- dog(477229) topoisomerase (DNA) I
- chicken(396004) topoisomerase (DNA) I
- Zebrafish(327179) topoisomerase (DNA) I
- domestic guinea pig(100716716) topoisomerase (DNA) I
- naked mole-rat(101704241) topoisomerase (DNA) I
- cow(534799) topoisomerase (DNA) I
- sheep(101103086) topoisomerase (DNA) I
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Antibodies
货号
说明
物种反应性
应用
抗拓扑异构酶I-DNA共价复合物抗体，克隆1.1A, clone 1.1A, from mouse,
物种反应性
human, mouse
应用
ELISA
dot blot
flow cytometry
immunocytochemistry
dot blot
flow cytometry
immunocytochemistry
Anti-TOP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-Topoisomerase I antibody produced in mouse, clone Mab1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
microarray
western blot
western blot
Anti-DNA topoisomerase I (TOP1) Antibody, clone 3D4W6, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Monoclonal Anti-TOP1 antibody produced in mouse, clone 1A1, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
货号
说明
物种
Topo I (197-651) (core domain) human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
物种
human
Topo I (N1-197) (NTD) human, recombinant, expressed in insect cells, ≥85% (SDS-PAGE),
物种
human
Topo I (C651-765) (C terminal domain) human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
物种
human
Topo I (Y723F) (mt Y723F) human, recombinant, expressed in insect cells, ≥80% (SDS-PAGE),
物种
human