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Merck

SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

别名:
EAAT2, GLT-1
物种:
UniProtKB ID:
基因ID:
  • Human(6506) Summary: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
  • Mouse(20511) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • Rat(29482) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • domestic guinea pig(100731435) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • naked mole-rat(101701278) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • cow(541119) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • chicken(423156) solute carrier family 1 (glial high affinity glutamate transporter), member 2
  • dog(403750) solute carrier family 1 (glial high affinity glutamate transporter), member 2

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Small Molecule - Antagonist

货号
说明
物种
L-trans-Pyrrolidine-2,4-dicarboxylic acid, ≥98%,
物种
rat
二氢红藻氨酸, ≥98% (HPLC), powder,
物种
rat, human
(±)-AMPA, solid,
物种
rat
红藻氨酸 一水合物, ≥99% (TLC),
物种
human, mouse, rat
氨甲基膦酸, 99%,
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
抗谷氨酸转运蛋白抗体,胶质细胞, serum, Chemicon®,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-Excitatory amino acid transporter 2 Antibody, clone G6, clone G6, from mouse,
物种反应性
human, mouse, rat
应用
immunocytochemistry
immunohistochemistry

western blot
Anti-SLC1A2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
Anti-SLC1A2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

货号
说明
物种
二氢红藻氨酸, ≥98% (HPLC), powder,
物种
rat, human
氨甲基膦酸, 99%,
物种
rat, human
L-谷氨酸, ReagentPlus®, ≥99% (HPLC),
物种
rat, human
L-谷氨酸, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
物种
rat, human
L-谷氨酸, BioUltra, ≥99.5% (NT),
物种
rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human SLC1A2,
物种
human