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Merck

SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

别名:
PI12, neuroserpin
物种:
UniProtKB ID:
基因ID:
  • Human(5274) Summary: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(20713) serine (or cysteine) peptidase inhibitor, clade I, member 1
  • Rat(116459) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • Zebrafish(557627) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • dog(478684) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • domestic cat(101090383) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • Horse(100057410) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • chicken(425002) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • Domestic Rabbit(100341797) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • naked mole-rat(101716288) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • domestic guinea pig(100733658) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • cow(509976) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • sheep(101122566) serpin peptidase inhibitor, clade I (neuroserpin), member 1

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Antibodies

货号
说明
物种反应性
应用
Anti-SERPINI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-SERPINI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Monoclonal Anti-SERPINI1, (C-terminal) antibody produced in mouse, clone 1E10, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-Neuroserpin antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
chimpanzee, human, mouse, rat
应用
ELISA
western blot
Monoclonal Anti-SERPINI1 antibody produced in mouse, clone 1D10, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot

Proteins

货号
说明
物种
Neuroserpin human, recombinant, expressed in E. coli, ≥96% (SDS-PAGE), ≥96% (HPLC), suitable for cell culture,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human SERPINI1,
物种
human
MISSION® esiRNA, targeting mouse Serpini1,
物种
mouse