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Merck

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

别名:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
物种:
Human PTGS2 (5743), Mouse Ptgs2 (19225), Rat Ptgs2 (29527), cow PTGS2 (282023), sheep PTGS2 (443460), Goat PTGS2 (100860905), naked mole-rat Ptgs2 (101704771), Domestic Rabbit PTGS2 (100009248), domestic guinea pig Ptgs2 (100135607), chicken PTGS2 (396451) ...展开
UniProtKB ID:
P35354, A8K802, Q16876
基因ID:
  • Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
  • Mouse(19225) prostaglandin-endoperoxide synthase 2
  • Rat(29527) prostaglandin-endoperoxide synthase 2
  • cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2
  • chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

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ELISA

货号
说明
物种
RAB1034
人COX-2 ELISA试剂盒, for cell culture supernatants, plasma, and serum samples,
物种
human

Antibodies

货号
说明
物种反应性
应用
240R-1
COX-2 (SP21) Rabbit Monoclonal Antibody, ,
物种反应性
human
应用
immunohistochemistry
SAB5702963
Anti-COX2/PTGS2 Antibody, clone 2V7G8, Rabbit Monoclonal, ,
物种反应性
mouse
应用
immunohistochemistry
western blot
SAB4502491
抗-COX2 兔抗, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB5700721
Anti-Cox2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA001335
抗-COX2 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

货号
说明
物种
T4376
N-对-甲苯磺酰基-L-苯基乙基氯甲基酮, ≥97% (TLC), powder,
物种
human

Small Molecule - Inhibitor

货号
说明
物种
SML1713
卡洛芬, ≥97% (HPLC),
物种
human
A8861
Aceclofenac, ≥98% (HPLC),
物种
human
1098504
塞来昔布, United States Pharmacopeia (USP) Reference Standard,
物种
human
1096699
卡洛芬, United States Pharmacopeia (USP) Reference Standard,
物种
human
32097
依托考昔, VETRANAL®, analytical standard,
物种
human

Proteins

货号
说明
物种
C0858
环氧化酶 2 人, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
物种
human

esiRNA

货号
说明
物种
EMU039641
MISSION® esiRNA, targeting mouse Ptgs2,
物种
mouse
EHU050311
MISSION® esiRNA, targeting human PTGS2,
物种
human