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Merck

PIAS2

protein inhibitor of activated STAT, 2

别名:
ARIP3, DIP, MIZ, MIZ1, PIASX, PIASX-ALPHA, PIASX-BETA, SIZ2, ZMIZ4
物种:
UniProtKB ID:
基因ID:
  • Human(9063) Summary: This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011]
  • Mouse(17344) protein inhibitor of activated STAT 2
  • Rat(83422) protein inhibitor of activated STAT, 2
  • Zebrafish(564149) protein inhibitor of activated STAT, 2
  • chicken(416383) protein inhibitor of activated STAT, 2
  • Horse(100068879) protein inhibitor of activated STAT, 2
  • domestic cat(101081835) protein inhibitor of activated STAT, 2
  • dog(480147) protein inhibitor of activated STAT, 2
  • domestic guinea pig(100718605) protein inhibitor of activated STAT, 2
  • naked mole-rat(101709303) protein inhibitor of activated STAT, 2
  • cow(533403) protein inhibitor of activated STAT, 2
  • sheep(101112782) protein inhibitor of activated STAT, 2

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Antibodies

货号
说明
物种反应性
应用
Anti-PIAS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Monoclonal Anti-PIAS2 antibody produced in mouse, clone 1F7, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
immunofluorescence

proximity ligation assay

western blot
Anti-PIAS2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
Anti-PIAS2 Antibody, clone 4I6K6, Rabbit Monoclonal, ,
物种反应性
mouse, rat
应用
western blot
Anti-PIAS2 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, dog, horse, human, rabbit
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PIAS2,
物种
human
MISSION® esiRNA, targeting mouse Pias2,
物种
mouse