跳转至内容
Merck

LCK

lymphocyte-specific protein tyrosine kinase

别名:
LSK, YT16, p56lck, pp58lck
物种:
Human LCK (3932), Mouse Lck (16818), Rat Lck (313050), sheep LCK (100216439), Domestic Rabbit LCK (100349102), domestic guinea pig Lck (100728811), naked mole-rat Lck (101714396), Zebrafish lck (414333), cow LCK (508890), Horse LCK (100146139) ...展开
UniProtKB ID:
P06239, D3DPP8, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q7RTZ3
基因ID:
  • Human(3932) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
  • Mouse(16818) lymphocyte protein tyrosine kinase
  • Rat(313050) lymphocyte-specific protein tyrosine kinase
  • sheep(100216439) lymphocyte-specific protein tyrosine kinase
  • Domestic Rabbit(100349102) lymphocyte-specific protein tyrosine kinase
  • domestic guinea pig(100728811) lymphocyte-specific protein tyrosine kinase
  • naked mole-rat(101714396) lymphocyte-specific protein tyrosine kinase
  • Zebrafish(414333) lymphocyte-specific protein tyrosine kinase
  • cow(508890) lymphocyte-specific protein tyrosine kinase
  • Horse(100146139) lymphocyte-specific protein tyrosine kinase
  • domestic cat(101098805) lymphocyte-specific protein tyrosine kinase
  • dog(478151) lymphocyte-specific protein tyrosine kinase
  • chicken(396460) lymphocyte-specific protein tyrosine kinase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

货号
说明
物种
RAB0974
磷酸酪氨酸LCK /酪氨酸蛋白激酶Lck ELISA试剂盒, ,
物种
human

Small Molecule - Antagonist

货号
说明
物种
536954
迷迭香酸, 96%,
物种
human
594687
α-六噻吩, ,
物种
human, rat

Antibodies

货号
说明
物种反应性
应用
06-583
抗Lck抗体, Upstate®, from rabbit,
物种反应性
human
应用
immunoprecipitation (IP)
western blot
SAB4300118
抗-磷酸-LCK (pTyr394) 兔抗, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
western blot
HPA003494
Anti-LCK antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
western blot
SAB4504459
Anti-phospho-Lck (pTyr393) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
western blot
SAB5701751
Anti-Phospho-LCK-Y394 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
249548
2-萘磺酸, technical grade, 70%,
物种
human
186341
1-萘磺酸, >50%,
物种
human
N5602
1-萘基磷酸酯, 99%,
物种
human
C8863
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
物种
human
CDS023580
帕唑帕尼, ,
物种
human

Proteins

货号
说明
物种
L2792
LCK，活性，GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
EMU068551
MISSION® esiRNA, targeting mouse Lck,
物种
mouse
EHU064811
MISSION® esiRNA, targeting human LCK,
物种
human