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Merck

KEAP1

kelch-like ECH-associated protein 1

别名:
INrf2, KLHL19
物种:
UniProtKB ID:
基因ID:
  • Human(9817) Summary: This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(50868) kelch-like ECH-associated protein 1
  • Rat(117519) Kelch-like ECH-associated protein 1
  • fruit fly(42062) CG3962 gene product from transcript CG3962-RC
  • cow(532791) kelch-like ECH-associated protein 1
  • dog(476713) kelch-like ECH-associated protein 1
  • domestic cat(101091260) kelch-like ECH-associated protein 1
  • sheep(101113845) kelch-like ECH-associated protein 1
  • domestic guinea pig(100713871) kelch-like ECH-associated protein 1
  • naked mole-rat(101718777) kelch-like ECH-associated protein 1

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Antibodies

货号
说明
物种反应性
应用
Anti-Keap1 Antibody, clone 144, clone 144, from rat,
物种反应性
human, mouse
应用
flow cytometry
immunocytochemistry

western blot
Anti-KEAP1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-KEAP1 (AB1) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, horse, human, mouse, pig, rabbit, rat
应用
immunohistochemistry
western blot
Anti-KEAP1 antibody produced in rabbit, IgG fraction of antiserum,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
Anti-KEAP1 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse, rat
应用
immunocytochemistry
western blot

Small Molecule - Inhibitor

货号
说明
物种
富马酸二甲酯, 97%,
物种
human
富马酸二甲酯, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
富马酸二甲酯, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
物种
human
CDDO 甲酯, ≥98% (HPLC),
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human KEAP1,
物种
human