GSTM4
glutathione S-transferase mu 4
别名:
GSTM4-4, GTM4
物种:
Human GSTM4 (2948), Mouse Gstm4 (14865), Rat Gstm4 (499689), dog GSTM4 (479912), domestic cat GSTM4 (101100824)
UniProtKB ID:
基因ID:
- Human(2948) Summary: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified. [provided by RefSeq, Jul 2008]
- Mouse(14865) glutathione S-transferase, mu 4
- Rat(499689) glutathione S-transferase mu 4
- dog(479912) glutathione S-transferase mu 4
- domestic cat(101100824) glutathione S-transferase mu 4
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Monoclonal Anti-GSTM4 antibody produced in mouse, clone 4B4, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
western blot
Anti-GSTM4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot
Cell Lines
货号
说明
物种