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Merck

GRM6

glutamate receptor, metabotropic 6

别名:
CSNB1B, GPRC1F, MGLUR6, mGlu6
物种:
UniProtKB ID:
基因ID:
  • Human(2916) Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. [provided by RefSeq, Feb 2012]
  • Mouse(108072) glutamate receptor, metabotropic 6
  • Rat(24419) glutamate receptor, metabotropic 6
  • dog(481452) glutamate receptor, metabotropic 6
  • cow(529656) glutamate receptor, metabotropic 6
  • domestic cat(101097449) glutamate receptor, metabotropic 6
  • domestic guinea pig(100722389) glutamate receptor, metabotropic 6
  • naked mole-rat(101717017) glutamate receptor, metabotropic 6

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Small Molecule - Agonist

货号
说明
物种
D-2-Aminoadipic acid, ,
物种
rat
L -2-氨基己二酸, ≥98% (TLC),
物种
rat, human
反式-(±)-ACPD 一水合物, solid, ≥97% (NMR),
物种
human
L-(+)-2-氨基-4-膦酰基丁酸, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
物种
rat, human
(S)-AMPA, ≥97%,
物种
mouse, human, rat

Small Molecule - Antagonist

货号
说明
物种
D-2-Aminoadipic acid, ,
物种
rat
DL-2-Amino-3-phosphonopropionic acid, ,
物种
human
(S)-AMPA, ≥97%,
物种
mouse, human, rat
L-谷氨酸, ReagentPlus®, ≥99% (HPLC),
物种
rat, human
L-谷氨酸, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
物种
rat, human

Antibodies

货号
说明
物种反应性
应用
Anti-MGLUR6 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-Metabotropic Glutamate Receptor 6 Antibody, Chemicon®, from rabbit,
物种反应性
human
应用
immunohistochemistry
Anti-GRM6 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
immunohistochemistry
Monoclonal Anti-GRM6 antibody produced in mouse, clone 1A11, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-GRM6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunohistochemistry

Small Molecule - Mixed Agonist/Antagonist

货号
说明
物种
L-(+)-2-氨基-4-膦酰基丁酸, optical purity optical purity: ≥95% (HPLC, Marfey′s reagent),
物种
rat, human
L-谷氨酸, ReagentPlus®, ≥99% (HPLC),
物种
rat, human
L-谷氨酸, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
物种
rat, human
L-谷氨酸, BioUltra, ≥99.5% (NT),
物种
rat, human
L-谷氨酸, FCC,
物种
rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GRM6,
物种
human
MISSION® esiRNA, targeting mouse Grm6,
物种
mouse