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Merck

F9

coagulation factor IX

别名:
FIX, HEMB, P19, PTC, THPH8
物种:
UniProtKB ID:
基因ID:
  • Human(2158) Summary: This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. [provided by RefSeq, Jul 2008]
  • Mouse(14071) coagulation factor IX
  • Rat(24946) coagulation factor IX
  • chicken(374258) coagulation factor IX
  • dog(404015) coagulation factor IX
  • domestic cat(493973) coagulation factor IX
  • cow(280688) coagulation factor IX
  • Horse(100054449) coagulation factor IX
  • domestic guinea pig(100135464) coagulation factor IX
  • naked mole-rat(101724977) coagulation factor IX
  • sheep(443316) coagulation factor IX
  • Domestic Rabbit(100009113) coagulation factor IX

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Antibodies

货号
说明
物种反应性
应用
抗-因子IX抗体,小鼠单克隆, clone HIX-1, purified from hybridma cell culture,
物种反应性
human
应用
ELISA
western blot
Anti-Factor IX antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human
应用
ELISA
dot blot

western blot
Anti-Factor IX antibody, Mouse monoclonal, clone HIX-5, purified from hybridoma cell culture,
物种反应性
human
应用
ELISA
western blot

Proteins

货号
说明
物种
IX 因子 人, aqueous glycerol solution, ≥145 units/mg protein,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human F9,
物种
human