CREBBP
CREB binding protein
别名:
CBP, KAT3A, RSTS
物种:
Human CREBBP (1387), Mouse Crebbp (12914), Rat Crebbp (54244), Zebrafish crebbp (100535787), dog CREBBP (479866), Horse CREBBP (100069613), domestic cat CREBBP (101094471), chicken CREBBP (416667), cow CREBBP (505453), naked mole-rat Crebbp (101714025) ...展开
UniProtKB ID:
基因ID:
- Human(1387) Summary: This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
- Mouse(12914) CREB binding protein
- Rat(54244) CREB binding protein
- Zebrafish(100535787) CREB binding protein
- dog(479866) CREB binding protein
- Horse(100069613) CREB binding protein
- domestic cat(101094471) CREB binding protein
- chicken(416667) CREB binding protein
- cow(505453) CREB binding protein
- naked mole-rat(101714025) CREB binding protein
- domestic guinea pig(100716770) CREB binding protein
- sheep(101123600) CREB binding protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-CREBBP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-CREB-BP antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-CBP Antibody, clone 3N20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
human, rat
应用
affinity binding assay
immunocytochemistry
immunohistochemistry
immunocytochemistry
immunohistochemistry
Anti-CBP antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-CREBBP antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
immunohistochemistry
western blot
western blot
Proteins
货号
说明
物种
CBP (1319-1710), GST tagged human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
KAT3A (518-1207), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human