跳转至内容
Merck

ARHGEF7

Rho guanine nucleotide exchange factor (GEF) 7

别名:
BETA-PIX, COOL-1, COOL1, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB
物种:
UniProtKB ID:
基因ID:
  • Human(8874) Summary: Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(54126) Rho guanine nucleotide exchange factor (GEF7)
  • Rat(114559) Rho guanine nucleotide exchange factor (GEF) 7
  • chicken(418761) Rho guanine nucleotide exchange factor (GEF) 7
  • cow(524352) Rho guanine nucleotide exchange factor (GEF) 7
  • Horse(100066489) Rho guanine nucleotide exchange factor (GEF) 7
  • domestic cat(101090075) Rho guanine nucleotide exchange factor (GEF) 7
  • dog(485552) Rho guanine nucleotide exchange factor (GEF) 7
  • sheep(101116845) Rho guanine nucleotide exchange factor (GEF) 7
  • naked mole-rat(101713994) Rho guanine nucleotide exchange factor (GEF) 7
  • domestic guinea pig(100717780) Rho guanine nucleotide exchange factor (GEF) 7

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

货号
说明
物种反应性
应用
Anti-Beta Pix, SH3 Domain Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, mouse, rat
应用
western blot
Anti-ARHGEF7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-ARHGEF7 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human ARHGEF7,
物种
human
MISSION® esiRNA, targeting mouse Arhgef7,
物种
mouse