ABI1
abl-interactor 1
别名:
ABI-1, ABLBP4, E3B1, NAP1BP, SSH3BP, SSH3BP1
物种:
Human ABI1 (10006), Mouse Abi1 (11308), Rat Abi1 (79249), Thale Cress ABI1 (828714), dog ABI1 (607247), Horse ABI1 (100055377), cow ABI1 (540815), domestic cat ABI1 (101082922), chicken ABI1 (420489), naked mole-rat Abi1 (101724965) ...展开
UniProtKB ID:
基因ID:
- Human(10006) Summary: This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
- Mouse(11308) abl-interactor 1
- Rat(79249) abl-interactor 1
- Thale Cress(828714) protein phosphatase 2C 56
- dog(607247) abl-interactor 1
- Horse(100055377) abl-interactor 1
- cow(540815) abl-interactor 1
- domestic cat(101082922) abl-interactor 1
- chicken(420489) abl-interactor 1
- naked mole-rat(101724965) abl-interactor 1
- domestic guinea pig(100720396) abl-interactor 1
- Domestic Rabbit(100349265) abl-interactor 1
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Antibodies
货号
说明
物种反应性
应用
Anti-ABI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-Abl (c-, v-, Bcr-) Antibody, clone 24-21, clone 24-21, from mouse,
物种反应性
human
应用
immunocytochemistry
western blot
western blot
Anti-ABI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
western blot
western blot
Anti-phospho-Abi-1 (Ser225) Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human, monkey, mouse, rat
应用
western blot
Anti-phospho-Abl (Tyr412) Antibody, Upstate®, from rabbit,
物种反应性
human, mouse, rat
应用
ELISA
western blot
western blot
esiRNA
货号
说明
物种