SML3485
PFI-7 hydrochloride
≥98% (HPLC)
Synonym(s):
N-((1s,4s)-4-(1H-Benzo[d]imidazol-2-yl)cyclohexyl)-2-((1H-indol-2-yl)methylamino)acetamide hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C24H27N5O · xHCl
Molecular Weight:
401.50 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.28
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Quality Level
Assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
H2O: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C(CNCC1=CC2=C(N1)C=CC=C2)N[C@@H]3CC[C@@H](CC3)C4=NC5=C(N4)C=CC=C5
Biochem/physiol Actions
PFI-7 is a high affinity E3 ligase GID4 probe (KD = 0.08 μM by SPR) that competes against cellular degrons for full-length GID4 binding with high potency (EC50 = 0.6 μM by cell-based NanoBRET).
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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