SCP0191

MMP 2 / MMP 9 Substrate

• Empirical Formula (Hill Notation): C₄₄H₆₁N₁₃O₁₃S₁
• Molecular Weight: 1012.10
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• Assay: ≥95% (HPLC)
• form: lyophilized
• composition: Peptide Content, ≥78%
• storage condition: protect from light
• storage temp.: −20°C

Description

Amino Acid Sequence

DNP-Pro-Leu-Gly-Met-Trp-Ser-Arg

Application

Matrix metalloproteinases (MMP) are a family of zinc-dependent endopeptidases that degrade matrix proteins. MMPs include collagenases, gelatinases, matrilysins, enamelysins, metalloelastases, stromelysins and other structural protein and receptor lysins. The activity of these enzymes is selectively inhibited or measured by appropriately labeled peptides. DNP-Pro-Leu-Gly-Met-Trp-Ser-Arg (DNP-PLGMWSR), Dnp-Pro-Leu-Gly-Leu-Trp-Ala-D-Arg-NH2 (DNP-PLGLWA-D-R-NH2), Dnp-Pro-Gln-Gly-Ile-Ala-Gly-Gln-D-Arg-OH (DNP-PQGIAGQ-D-R-OH) and MOCAc [(7-methoxy coumarin-4-yl) acetyl]-RPKPYANvaWMK(Dnp[2,4-dinitrophenyl])-NH(2) are substrates for matrix metalloproteinase 2 and matrix metalloproteinase 9.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable