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Key Documents

SAB5702088

Sigma-Aldrich

Anti-HSD3B1 Antibody, clone 3F2Z7, Rabbit Monoclonal

Synonym(s):

HSD3B1, 3BETAHSD, HSD3B, HSDB3, HSDB3A, I, SDR11E1, 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46

biological source

rabbit

Quality Level

material

colorless

clone

3F2Z7, monoclonal

form

liquid

mol wt

42 kDa

species reactivity

rat, human, rat

concentration

1.5 mg/mL

technique(s)

immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000

color

colorless

isotype

IgG

immunogen sequence

RGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMYWIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAK

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HSD3B1(3283)

General description

The protein encoded by this gene is an enzyme that catalyzes the oxidative conversion of delta-5-3-beta-hydroxysteroid precursors into delta-4-ketosteroids, which leads to the production of all classes of steroid hormones. The encoded protein also catalyzes the interconversion of 3-beta-hydroxy- and 3-keto-5-alpha-androstane steroids.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 250-350 of human HSD3B1 (P14060).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC

Storage Class Code

10 - Combustible liquids

WGK

WGK 1


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