SAB3500873
Monoclonal Anti-HEMAGGLUTININ antibody produced in mouse
clone 7B9B2, affinity isolated antibody
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About This Item
biological source
mouse
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
7B9B2, monoclonal
form
buffered aqueous solution
species reactivity
virus
concentration
1 mg/mL
technique(s)
ELISA: suitable
immunoblotting: suitable
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
Hemagglutinin [Influenza A virus (A/chicken/Jilin/9/ 2004(H5N1))] is the principal surface antigen of influenza A virus. Hemagglutinin (HA) is a homotrimer; each monomer is a single polypeptide (HA0) that is post transcriptionally cleaved by host proteases into two subunits (HA1 and HA2). HA2 is highly conserved across different strains of influenza virus. HA preferentially binds to α2-3 sialic acid receptor in aves, whereas in human it binds to α2-6 sialic acid receptor.
Immunogen
Antibody was raised against a peptide corresponding to 13 amino acids in the middle of the Hemagglutinin protein.
Biochem/physiol Actions
Hemagglutinin (HA), specially HA2 is responsible for the binding of the virus to host receptors and enables its entry into the host cell through endocytosis through endosomal membrane fusion. HA is the primary target for neutralizing antibodies. HA is a potent target for drug and vaccine development.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 1 mg/mL in PBS with 0.02% sodim azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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