Skip to Content
Merck
All Photos(1)

Key Documents

RAB1092

Sigma-Aldrich

Human TSG-6 ELISA Kit

for cell culture supernatants, plasma, and serum samples

Synonym(s):

Hyaluronate-binding protein, TSG-6, Tumor necrosis factor-inducible gene 6 protein 

Sign Into View Organizational & Contract Pricing


About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type serum sample(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.2 ng/ml

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TNFAIP6(7130)

General description

This ELISA antibody pair detects human TSG-6. Other species not yet determined.

Application

Human TSG-6 ELISA Kit has been used to determine galectin G3 and intermediate metabolites level.

Biochem/physiol Actions

Tumor necrosis factor (TNF)-α–stimulated gene 6 protein (TSG-6) has been implicated in regulation of cell-cell and cell-matrix interactions during inflammation and tumorigenesis. TSG-6 possess anti-inflammatory properties. It is also known to reduce inflammatory reactions triggered by ischemia in the heart. Thus, it might have a potential role in treating heart disease with other cells such as skeletal myoblasts, fetal myoblasts and embryonic stem cells.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pictograms

Corrosion

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

The value of determination of galectin-3 and midkine in serum of patients with thyroid cancer for the evaluation of tumor condition.
Liu Y, et al.
Journal of Hainan Medical College, 3, 38-38 (2017)
Reiko Iwazawa et al.
Cell transplantation, 27(9), 1390-1400 (2018-07-07)
Cell therapies using adipose-derived stem cells (ADSCs) have been used to treat inflammatory bowel disease (IBD) in human and dog. We previously reported the CellSaic technique, which uses a recombinant scaffold to enhance the efficacy of cell therapy. To examine
Anti-inflammatory protein TSG-6 secreted by activated MSCs attenuates zymosan-induced mouse peritonitis by decreasing TLR2/NF-?B signaling in resident .
Hosoo , et al.
Blood, 118, 330-338 (2011)
S Keisin Wang et al.
The Journal of surgical research, 220, 311-319 (2017-11-29)
The formation of abdominal aortic aneurysms (AAA) is characterized by a dominance of proinflammatory forces that result in smooth muscle cell apoptosis, extracellular matrix degradation, and progressive diameter expansion. Additional defects in the antiinflammatory response may also play a role
Woo-Jin Song et al.
Research in veterinary science, 125, 176-184 (2019-06-28)
Canine inflammatory bowel disease (IBD) is an intractable autoimmune disorder that results in various gastrointestinal and systemic symptoms. Mesenchymal stem cells (MSCs), which release immunomodulatory factors such as tumor necrosis factor-α (TNF-α)-induced gene/protein 6 (TSG-6) and prostaglandin E2 (PGE2), have

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service