RAB0810
Mouse Il18 / Interleukin-18 ELISA Kit
for serum, plasma and cell culture supernatants
Synonym(s):
IFN-gamma-inducing factor, IL-18, Interleukin-18
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.15 ng/mL
standard curve range: 0.205-50 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Il18(16173)
General description
Interleukin-18 (IL-18) belongs to the IL-1 family of cytokines. It is synthesized as an inactive precursor and converted to the active form by caspase-1. IL-18 is involved in the synthesis of interferon-γ (IFN-γ) and IL-13 from T-cells and natural killer (NK) cells. It is a proinflammatory cytokine that aids in the activation of NK cells and T helper 1 cell response. The antibody pair provided in this kit recognizes mouse interleukin 18.
The antibody pair provided in this kit recognizes Mouse Interleukin 18.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Mouse Il18 / Interleukin-18 ELISA Kit has been used to detect interleukin-18 in serum samples.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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T Yoshimoto et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(24), 13962-13966 (1999-11-26)
IL-18 is a proinflammatory cytokine that plays an important role in natural killer cell activation and T helper 1 (Th1) cell responses. Mast cells and basophils are major inducers and effectors of allergic inflammation. Here we show that basophils and
Charles A Dinarello et al.
Frontiers in immunology, 4, 289-289 (2013-10-12)
Interleukin-18 (IL-18) is a member of the IL-1 family of cytokines. Similar to IL-1β, IL-18 is synthesized as an inactive precursor requiring processing by caspase-1 into an active cytokine but unlike IL-1β, the IL-18 precursor is constitutively present in nearly
Benjamin Uzan et al.
EMBO molecular medicine, 6(6), 821-834 (2014-04-30)
Development of novel therapies is critical for T-cell acute leukaemia (T-ALL). Here, we investigated the effect of inhibiting the MAPK/MEK/ERK pathway on T-ALL cell growth. Unexpectedly, MEK inhibitors (MEKi) enhanced growth of 70% of human T-ALL cell samples cultured on
Zufeng Ding et al.
Biochemical and biophysical research communications, 451(4), 637-643 (2014-08-19)
Lectin-like oxidized low-density lipoprotein scavenger receptor-1 (LOX-1) is known to be involved in many pathophysiological events, such as inflammation. To clarify the role of LOX-1 in mtDNA damage and NLRP3 inflammasome activation, we studied wild-type (WT) and LOX-1 knockout (KO)
Jin-Mei Chen et al.
Cytokine, 119, 113-118 (2019-03-25)
Recent studies have provided overwhelming evidence of the involvement of microglia-related molecular networks in the pathogenesis of Alzheimer's diseases (AD). The potential involvement of pro-inflammatory cytokines interleukin (IL)-18, IL-23 and IL-17 on amyloid (Aβ) clearance is still unclear. In this
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