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Key Documents

N9879

Sigma-Aldrich

NADase from porcine brain

≥0.007 unit/mg solid

Synonym(s):

DPN Nucleosidase, NAD+ glycohydrolase

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About This Item

CAS Number:
Enzyme Commission number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54

form

powder

Quality Level

specific activity

≥0.007 unit/mg solid

solubility

insoluble

storage temp.

−20°C

General description

NADase is a glycohydrolase that catalyzes ADP-ribose transfer.

Application

NADase from porcine brain has been used in a study to investigate histidine and related compounds resulting from catalyzed ADP-riboslyation. It has also been used in a study to investigate the preparation of arylazide-substituted pyridine adenine dinucleotides for photoaffinity labeling.

Biochem/physiol Actions

Nicotinamide has been shown to inhibit NADase activity.

Unit Definition

One unit will hydrolyze 1.0 μmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37 °C.

Physical form

Acetone-dried powder

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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