65906

Phalloidin–Atto 647N

BioReagent, suitable for fluorescence, ≥80% (HPLC)

• Synonym(s): Atto 647N, Atto 647N-Phalloidin
• UNSPSC Code: 12171501
• NACRES: NA.32

Properties

• product line: BioReagent
• Assay: ≥80% (HPLC)
• manufacturer/tradename: ATTO-TEC GmbH
• λ: in methanol
• UV absorption: λ: 640-646 nm A_max
• suitability: suitable for fluorescence
• detection method: fluorometric
• storage temp.: −20°C

Description

General description

Phalloidin–Atto 647N is a new fluorescentlabel targeting the red spectral region. Atto 647N is a cationic dye, and postcoupling, it carries a net electrical charge of +1.Like most Atto labels, the absorption andfluorescence of Atto 647N are independent of pH between 2-11. Atto 647N issupplied in the form of a mixture containing two isomers having identicalfluorescence and absorption properties. Atto labels have rigid structures thatdo not show any cis-trans-isomerization.

Application

Phalloidin–Atto 647Nis designed to be used for labelling DNA, RNA, or proteins. Fluorescentconjugates of phalloidin are used to label actin filaments for histologicalapplications. Some structural features of phalloidin are required for thebinding to actin.

Features and Benefits

Characteristic features of the Phalloidin Atto488 are:

1. StrongAbsorption.
2. HighFluorescence quantum yield.
3. HighPhotostability.
4. MinimalTriplet formation.
5. GoodSolubility.
6. Excellent Ozone Resistance.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H300 + H310 + H330
• Precautionary Statements: P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310
• Hazard Classifications: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral
• Storage Class Code: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves