389M-1

Glutamine Synthetase (GS-6) Mouse Monoclonal Antibody

• UNSPSC Code: 12352116
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100; 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: GS-6, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (389M-14); vial of 0.5 mL concentrate (389M-15); bottle of 1.0 mL predilute (389M-17); vial of 1.0 mL concentrate (389M-16); bottle of 7.0 mL predilute (389M-18)
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
• isotype: IgG2a
• control: hepatocellular carcinoma
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic
• Gene Information: human ... GLUL(2752)

Description

General description

Glutamine synthetase (GS) catalyzes the synthesis of glutamine from glutamate and ammonia in the mammalian liver. In normal liver, GS expression is seen in centrilobular (zone 3) hepatocytes, but not in mid-zone (zone 2) or periportal (zone 3) hepatocytes. Glutamine synthetase immunohistochemistry is also positive in neoplasms of hepatocyte origin, such as hepatocellular carcinoma (HCC) and hepatocellular adenoma, making it useful for identifying these tumors.

Quality

IVD

IVD

IVD

RUO

Linkage

Glutamine Synthetase Positive Control Slides, Product No. 389S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

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Other Notes

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