14879

BIS-TRIS

BioUltra, ≥99.0% (NT)

• Synonym(s): 2,2-Bis(hydroxymethyl)-2,2′,2″-nitrilotriethanol, 2-Bis(2-hydroxyethyl)amino-2-(hydroxymethyl)-1,3-propanediol, Bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane
• Empirical Formula (Hill Notation): C₈H₁₉NO₅
• CAS Number: 6976-37-0
• Molecular Weight: 209.24
• Beilstein: 2205275
• EC Number: 230-237-7
• MDL number: MFCD00002853
• UNSPSC Code: 12161700
• PubChem Substance ID: 57647226
• NACRES: NA.25

Properties

• product line: BioUltra
• Quality Level: 200
• Assay: ≥99.0% (NT)
• form: powder
• impurities: insoluble matter, passes filter test
• ign. residue: ≤0.3%
• loss: ≤0.5% loss on drying, 20 °C (HV)
• pH: 9.5-11.0 (25 °C, 1 M in H₂O)
• useful pH range: 5.8-7.2
• pKa (25 °C): 6.5
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤50 mg/kg; sulfate (SO₄^2-): ≤50 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• absorption: cut-off at 270 nm in H₂O at 1 M
• λ: 1 M in H₂O
• UV absorption: λ: 280 nm A_max: 0.1
• SMILES string: OCCN(CCO)C(CO)(CO)CO
• InChI: 1S/C8H19NO5/c10-3-1-9(2-4-11)8(5-12,6-13)7-14/h10-14H,1-7H2
• InChI key: OWMVSZAMULFTJU-UHFFFAOYSA-N

Description

Application

BIS-TRIS can be used to study biological buffers. BIS-TRIS has been used in a study that synthesized ferritin grafted with temperature-responsive poly(N-isopropylacrylamide) (PIPAAm-ferritin) by a coupling reaction using PIPAAm and ferritin for obtaining stimuli-responsive biomaterials. BIS-TRIS has also been used in a study that synthesized and described the photochemical properties of oligo- ortho –azobenzenes.

Other Notes

Easily compare specifications for BIS-TRIS products with the BIS-TRIS specification table.

Effective buffer for the assay of creatine kinase; Effectively protects hemoglobin during freeze-drying; Catholyte in IEF of 2-D gel electrophoresis.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H319
• Precautionary Statements: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves