14300
Betaine monohydrate
≥99.0% (NT)
Synonym(s):
1-carboxy-n,n,n-trimethylmethanaminium hydroxide, 2-(trimethylammonio)acetate hydrate, glycine betaine hydrate
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All Photos(3)
About This Item
Linear Formula:
(CH3)3N+CH2COO- · H2O
CAS Number:
Molecular Weight:
135.16
Beilstein:
3626258
EC Number:
MDL number:
UNSPSC Code:
51171529
PubChem Substance ID:
NACRES:
NA.25
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Quality Level
Assay
≥99.0% (NT)
form
solid
solubility
H2O: 0.1 g/mL, clear, colorless
storage temp.
2-8°C
SMILES string
O.C[N+](C)(C)CC([O-])=O
InChI
1S/C5H11NO2.H2O/c1-6(2,3)4-5(7)8;/h4H2,1-3H3;1H2
InChI key
NJZRLXNBGZBREL-UHFFFAOYSA-N
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Application
Betaine monohydrate:
- is suitable for use to improve the PCR amplification of GC-rich DNA sequences by reducing the formation of secondary structure caused by GC-rich regions
- is suitable for use as a component of PCR reaction mixture
- is suitable for use in a study to identify yield enhancers of PCR
- has been used to study nitrogen balance and nutrient digestibility in piglets fed diets deficient in methionine and low in compatible osmolytes
- has also been used to compare the effects of pressure on three layered hydrates
Biochem/physiol Actions
End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Cletus Nunes et al.
Journal of pharmaceutical sciences, 93(1), 38-47 (2003-12-04)
The objectives were (1). to perform solid-state characterization of anhydrous betaine (A) and betaine monohydrate (M), (2). to develop a pressure differential scanning calorimetric (DSC) technique for the quantification of M when present as a minor component in a mixture
Meike Eklund et al.
Archives of animal nutrition, 60(4), 289-300 (2006-08-23)
A balance experiment was carried out to investigate the effects of betaine monohydrate (BET) or betaine derived from condensed molasses solubles (CMS) as a substitute for methionine and choline on nitrogen (N) balance and total tract nutrient digestibility in weaned
Theodore Spilker et al.
Journal of clinical microbiology, 50(9), 3010-3015 (2012-07-13)
The genus Achromobacter currently is comprised of seven species, including Achromobacter xylosoxidans, an opportunistic and nosocomial pathogen that displays broad-spectrum antimicrobial resistance and is recognized as causing chronic respiratory tract infection in persons with cystic fibrosis (CF). To enable strain
Russell D L Johnstone et al.
Acta crystallographica. Section B, Structural science, 65(Pt 6), 731-748 (2009-11-20)
We report the effect of pressure on the crystal structures of betaine monohydrate (BTM), L-cysteic acid monohydrate (CAM) and S-4-sulfo-L-phenylalanine monohydrate (SPM). All three structures are composed of layers of zwitterionic molecules separated by layers of water molecules. In BTM
W Henke et al.
Nucleic acids research, 25(19), 3957-3958 (1997-10-10)
Betaine improves the co-amplification of the two alternatively spliced variants of the prostate-specific membrane antigen mRNA as well as the amplification of the coding cDNA region of c-jun. It is suggested that betaine improves the amplification of these genes by
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