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F5879

Sigma-Aldrich

Ammonium iron(III) citrate

reagent grade, powder

Synonym(s):

Ammonium ferric citrate, Ferric ammonium citrate

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About This Item

Linear Formula:
C6H8O7 ·xFe3+ · yNH3
CAS Number:
1185-57-5
EC Number:
214-686-6
UNSPSC Code:
12352300
eCl@ss:
38190508
PubChem Substance ID:
24894895
NACRES:
NA.55

grade

reagent grade

Quality Level

200

form

powder

composition

Iron, 16.5-18.5%

cation traces

Fe: 16.5-18.5%

SMILES string

N.OC12CC(=O)O[Fe](OC(=O)C1)OC(=O)C2

InChI

1S/C6H8O7.Fe.H3N/c7-3(8)1-6(13,5(11)12)2-4(9)10;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;1H3/q;+3;/p-3

InChI key

FRHBOQMZUOWXQL-UHFFFAOYSA-K

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General description

Ammonium iron(III)citrate can be used as a reagent and iron precursor in several organic reactions and Fe3O4-based nanomaterial preparation. It can be prepared by treating Fe(OH)3 with citric acid and NH4OH in various ratios.

Application

Ammonium iron(III) citrate can be used as a reagent to prepare amphiphilic siderophore iron acinetoferrin complex from acinetoferrin in the presence of HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) buffer. It can also be used as an iron precursor to prepare Fe3O4-carbon dots magnetic-fluorescent hybrid nanoparticles.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Hepcidin regulates systemic iron homeostasis. Suppression of hepcidin expression occurs physiologically in iron deficiency and increased erythropoiesis but is pathologic in thalassemia and hemochromatosis. Here we show that epigenetic events govern hepcidin expression. Erythropoiesis and iron deficiency suppress hepcidin via
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Antioxidants & redox signaling, 13(7), 999-1009 (2010-04-22)
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