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02575

Supelco

Dichloromethane

analytical standard

Synonym(s):

Methylene chloride

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About This Item

Empirical Formula (Hill Notation):
CH2Cl2
CAS Number:
Molecular Weight:
84.93
Beilstein:
1730800
EC Number:
MDL number:
UNSPSC Code:
12352101
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

vapor density

2.9 (vs air)

vapor pressure

24.45 psi ( 55 °C)
6.83 psi ( 20 °C)

Assay

≥99.9% (GC)

autoignition temp.

1223 °F

shelf life

limited shelf life, expiry date on the label

contains

0.002% amylene as stabilizer

expl. lim.

22 %

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.424 (lit.)
n20/D 1.424

bp

39.8-40 °C (lit.)

mp

−95 °C (lit.)

density

1.325 g/mL at 25 °C (lit.)

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

ClCCl

InChI

1S/CH2Cl2/c2-1-3/h1H2

InChI key

YMWUJEATGCHHMB-UHFFFAOYSA-N

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General description

Dichloromethane (methylene chloride) is a clear, colorless, non-flammable, volatile liquid chlorinated hydrocarbon with a sweet, pleasant smell and emits highly toxic fumes of phosgene when heated to decomposition. It is primarily used as a solvent in paint removers, in aerosol formulations, and as a solvent in the manufacture of pharmaceuticals. It is also used as a degreasing agent in electronics manufacturing and as an ethane foam blowing agent. Above all that it is used as an extraction solvent in the preparation of decaffeinated coffee, hop extracts and spice oleoresins.

Application

Dichloromethane may be used as an analytical reference standard for the determination of the analyte in spice oleoresins, biological samples as well as decaffeinated instant and ground coffee samples by gas chromatography (GC) technique.

Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 2

Flash Point(F)

does not flash

Flash Point(C)

does not flash

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Gas chromatographic determination of residual methylene chloride and trichloroethylene in decaffeinated instant and ground coffee with electrolytic conductivity and electron capture detection
Page BD and Charbonneau CF
Journal of the Association of Official Analytical Chemists, 60(3), 710-715 (1977)
Determination of methylene chloride, ethylene dichloride, and trichloroethylene as solvent residues in spice oleoresins, using vacuum distillation and electron capture gas chromatography
Page BD and Kennedy BPC
Journal of the Association of Official Analytical Chemists, 58(5), 1062-1068 (1975)
Guides, indexes, directory
Stellman, Jeanne Mager
Encyclopaedia of Occupational Health and Safety: Guides, indexes, directory, Jan 01, 104-104 (1998)
Capillary gas chromatography with cryogenic oven temperature for headspace samples: analysis of chloroform or methylene chloride in whole blood
Watanabe K, et al.
Analytical Chemistry, 69(24), 5178-5181 (1997)
Jeanne Mager Stellman
Encyclopaedia of Occupational Health and Safety: Guides, indexes, directory, 104, 242-242 (1998)

Articles

The Utility of Headspace Grade Solvents for the Analysis of Organic Volatile Impurities

Protocols

GC Analysis of Class 2 Residual Solvents on OVI-G43

US EPA Method TO-17: GC Analysis of Volatiles on VOCOL® after Collection/Desorption using Air Toxics Tube

US EPA Method 8260 describes the analysis of volatile organic compounds in solid wastes and ground waters. This application illustrates the analysis of many compounds commonly analyzed by this method using purge and trap coupled to GC-MS.

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