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Key Documents

MAB80138

Sigma-Aldrich

Anti-Human Metapneumovirus Antibody, clone 507

clone 507, Chemicon®, from mouse

Synonym(s):

hMPV

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

507, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable
western blot: suitable

isotype

IgG2a

shipped in

wet ice

General description

Human metapneumovirus (hMPV) is a member of the pneumovirinae subfamily of paramyxoviruses, first described in 2001 from pediatric respiratory specimens in the Netherlands. It is an enveloped pleomorphic virus with a single negative-strand RNA genome. Two major serotypes, A and B, have been described. Several studies identified hMPV in specimens worldwide, and estimated that by age 5 years 70% of children have developed antibodies to hMPV.

Specificity

Recognizes the nuclear protein. Reactive with all hMPV sub-types; A1, A2, B1, B2.

Application

Detect Human Metapneumovirus using this Anti-Human Metapneumovirus Antibody, clone 507 validated for use in ELISA, FC, IF & WB.

Physical form

Format: Purified

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999.
Chung-Guei Huang,Kuo-Chien Tsao,Tzou-Yien Lin,Yhu-Chering Huang,Li-Ang Lee,Tzu-Hou Chen et al.
Archives of Virology null
Analysis of the genomic sequence of a human metapneumovirus
van den Hoogen, Bernadette G, et al
Virology, 295, 119-132 (2002)
B G van den Hoogen et al.
Nature medicine, 7(6), 719-724 (2001-06-01)
From 28 young children in the Netherlands, we isolated a paramyxovirus that was identified as a tentative new member of the Metapneumovirus genus based on virological data, sequence homology and gene constellation. Previously, avian pneumovirus was the sole member of
Roles of the putative integrin-binding motif of the human metapneumovirus fusion (f) protein in cell-cell fusion, viral infectivity, and pathogenesis.
Wei, Y; Zhang, Y; Cai, H; Mirza, AM; Iorio, RM; Peeples, ME; Niewiesk, S; Li, J
Journal of virology null

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