8.52340
N-Biotinyl-NH(PEG)11-COOH
Novabiochem®
Synonym(s):
N-Biotinyl-NH(PEG)11-COOH, O-[2-(Biotinylamino)ethyl]-OÆ-(2-carboxyethyl)undecaethylene glycol
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About This Item
Empirical Formula (Hill Notation):
C37H69N3O16S
Molecular Weight:
844.02
UNSPSC Code:
12352106
NACRES:
NA.22
Quality Level
product line
Novabiochem®
Assay
≥98% (TLC)
form
powder
reaction suitability
reaction type: Biotinylations
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
storage temp.
15-25°C
General description
The use of this novel biotin derivative incorporates a hydrophilic 40 atom PEG spacer between the peptide and biotin. This not only greatly improves the solubility of the resultant peptide, but reduces steric hindrance between the peptide and biotin, leading to better avidin binding and higher biological activity. The biotin-PEG derivative can be easily incorporated using any standard coupling method as the final step in SPPS, immediately prior to cleavage of the peptide from the resin.
Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis
Associated Protocols and Technical Articles
Biotinylation Reagents for Peptide Synthesis
Analysis Note
Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 98 %
Identity (LC-MS): 843.0 - 845.0 g/mol
To see the solvent systems used for TLC of Novabiochem® products please click here.
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 98 %
Identity (LC-MS): 843.0 - 845.0 g/mol
To see the solvent systems used for TLC of Novabiochem® products please click here.
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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