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Key Documents

1.04302

Sigma-Aldrich

Hematoxylin cryst. (C.I. 75290)

for microscopy

Synonym(s):

Hematoxylin cryst. (C.I. 75290)

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About This Item

Empirical Formula (Hill Notation):
C16H14O6
CAS Number:
517-28-2
Molecular Weight:
302.28
MDL number:
MFCD00078111
UNSPSC Code:
41116130
EC Index Number:
208-237-3
NACRES:
NA.21

Quality Level

400

form

solid

IVD

for in vitro diagnostic use

visual transition interval

5.0-7.2, yellow to violet

mp

140 °C (Elimination of water of crystallisation)

bulk density

500 kg/m3

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-30°C

InChI

1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m1/s1

InChI key

WZUVPPKBWHMQCE-CJNGLKHVSA-N

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General description

Hematoxylin crystals are a dye for the specific staining of DNA in the nuclei. It is used in cytology and histology. Nuclei are stained blue, dark violet to black. Hematoxylins are mixed with trivalent positively charged metal salts and build up the so-called hematoxylin lakes, used for the selective staining of nuclei (DNA) .
It is an IVD registered product and CE certified, thus can be used for clinical diagnostic purposes. For more details, please see instructions for use (IFU).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Anna-Lena Ruppert et al.
Journal of molecular histology, 51(4), 421-435 (2020-07-04)
Tuft cells are a rare population of chemosensory cells at the mucosal surface epithelia of hollow organs. Their name-giving morphological feature is an apical tuft of stiff microvilli. Accordingly, the actin-binding protein, villin, was identified as one of the first

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