999991P
Avanti
18:0 Diether PC
1,2-di-O-octadecyl-sn-glycero-3-phosphocholine, powder
Synonym(s):
1,2-di-O-SPC
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About This Item
Empirical Formula (Hill Notation):
C44H92NO6P
CAS Number:
Molecular Weight:
762.18
UNSPSC Code:
51191904
NACRES:
NA.25
Recommended Products
form
powder
packaging
pkg of 1 × 10 mg (999991P-10mg)
pkg of 1 × 500 mg (999991P-500mg)
manufacturer/tradename
Avanti Polar Lipids 999991P
lipid type
cardiolipins
phospholipids
shipped in
dry ice
storage temp.
−20°C
SMILES string
[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OCCCCCCCCCCCCCCCCCC)COCCCCCCCCCCCCCCCCCC)=O
General description
18:0 Diether PC (phosphocholine) is a class of glycerophospholipids that has two octadecane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has choline as the alcohol moiety, attached to the phosphate group.
Application
18:0 Diether PC or 1,2-di-O-octadecyl-sn-glycero-3-phosphocholine might be used:
- as a nonhydrolizable ether lipid in calcein-containing vesicles for calcein encapsulation
- to prepare ether-linked phospholipid bilayer membrane for examining its thermotropic and barotropic phase transitions
- as a component of internal standard mixture for lipid extraction from plasma sample using mass spectromety
Packaging
20 mL Clear Glass Screw Cap Vial (999991P-500mg)
5 mL Amber Glass Screw Cap Vial (999991P-10mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Domain-induced activation of human phospholipase A2 type IIA: local versus global lipid composition.
Chad Leidy et al.
Biophysical journal, 90(9), 3165-3175 (2006-02-08)
Secretory human phospholipase A2 type IIA (PLA2-IIA) catalyzes the hydrolysis of the sn-2 ester bond in glycerolipids to produce fatty acids and lysolipids. The enzyme is coupled to the inflammatory response, and its specificity toward anionic membrane interfaces suggests a
Juergen Graessler et al.
PloS one, 4(7), e6261-e6261 (2009-07-16)
Dyslipoproteinemia, obesity and insulin resistance are integrative constituents of the metabolic syndrome and are major risk factors for hypertension. The objective of this study was to determine whether hypertension specifically affects the plasma lipidome independently and differently from the effects
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