999985P
Avanti
4ME 16:0 Diether PE
Avanti Polar Lipids 999985P, powder
Synonym(s):
1,2-di-O-phytanyl-sn-glycero-3-phosphoethanolamine
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About This Item
Empirical Formula (Hill Notation):
C45H94NO6P
CAS Number:
Molecular Weight:
776.20
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
form
powder
packaging
pkg of 1 × 25 mg (999985P-25mg)
pkg of 1 × 5 mg (999985P-5mg)
manufacturer/tradename
Avanti Polar Lipids 999985P
shipped in
dry ice
storage temp.
−20°C
SMILES string
[H][C@@](COP([O-])(OCC[NH3+])=O)(OCCC(C)CCCC(C)CCCC(C)CCCC(C)C)COCCC(C)CCCC(C)CCCC(C)CCCC(C)C
General description
4ME 16:0 Diether PE or 1,2-di-O-phytanyl-sn-glycero-3-phosphoethanolamine is a class of glycerophospholipids having two phytane chains attached to the sn-1 and sn-2 positions of the glycerol backbone by ether bonds. It has ethanolamine as the alcohol moiety, attached to the phosphate group.
Application
4ME 16:0 Diether PE or 1,2-di-O-phytanyl-sn-glycero-3-phosphoethanolamine is suitable:
- for nanoformulation of liposomal docosahexaenoic acid (DHA) and ghost (no DHA, control) liposomes
- for the preparation of archaeal-like lipid bilayers to examine the effect of humidity and temperature on it
- as an internal standard in tandem mass spectrometry/mass spectrometry/mass spectrometry (MS3) to study the effect on glycerophosphoethanolamine (GPEtn) species upon the exposure of human polymorphonuclear leukocytes to A23187 and granulocyte macrophage–colony-stimulating factor/formyl-methionyl-leucyl-phenylalanine stimuli
- as an internal standard in lipid extraction using methyl-tert-butylether (MTBE)/methanol protocol
Packaging
5 mL Clear Glass Sealed Ampule (999985P-25mg)
5 mL Clear Glass Sealed Ampule (999985P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Certificates of Analysis (COA)
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Christine G Skibinski et al.
Chemico-biological interactions, 252, 1-8 (2016-04-05)
The risk of breast cancer can be influenced by certain dietary components, such as the amount and type of dietary fatty acids ingested. Docosahexaenoic acid (DHA), a component of fish oil, is known to suppress rat mammary carcinogenesis, reduce cell
Marta Salvador-Castell et al.
Biochimica et biophysica acta. Biomembranes, 1862(2), 183130-183130 (2019-11-18)
It is now well established that cell membranes are much more than a barrier that separate the cytoplasm from the outside world. Regarding membrane's lipids and their self-assembling, the system is highly complex, for example, the cell membrane needs to
Structural Characterization of an Archaeal Lipid Bilayer as a Function of Hydration and Temperature.
Marta Salvador-Castell et al.
International journal of molecular sciences, 21(5) (2020-03-12)
Archaea, the most extremophilic domain of life, contain ether and branched lipids which provide extraordinary bilayer properties. We determined the structural characteristics of diether archaeal-like phospholipids as functions of hydration and temperature by neutron diffraction. Hydration and temperature are both
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