857133C

18:1 BMP (S,R)

bis(monooleoylglycero)phosphate (S,R Isomer) (ammonium salt), chloroform

• Synonym(s): sn-(3--(9Z-octadecenoyl)-2-hydroxy)-glycerol-1-phospho-sn-3′-(1′--(9Z-octadecenoyl)-2′-hydroxy)-glycerol (ammonium salt); lysobisphosphatidic acid; LBPA; 110729
• Empirical Formula (Hill Notation): C₄₂H₈₂NO₁₀P
• CAS Number: 326495-20-9
• Molecular Weight: 792.07
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (BMP (contains 30% positional isomers), TLC)
• form: liquid
• packaging: pkg of 1 × 1 mL (857133C-5mg); pkg of 1 × 2 mL (857133C-50mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 857133C
• concentration: 25 mg/mL (857133C-50mg); 5 mg/mL (857133C-5mg)
• lipid type: cardiolipins; phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP(OC[C@@]([H])(O)COC(CCCCCCC/C=C\CCCCCCCC)=O)([O-])=O)(O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[NH4+]

Description

General description

Bis(monoacylglycerol)phosphate (BMP), an acidic phospholipid is mostly found in the lysosomal and endosomal compartments within cells.

Application

18:1 BMP (S,R) is suitable for the analysis of Niemann-Pick C2 (NPC2)-lipid interaction.

Biochem/physiol Actions

Bis(monoacylglycerol)phosphate (BMP) plays a vital role in late endosomes/lysosomes (LE/Lys) degradation pathway. It is involved in digestion and recycling of membranous materials and synthesis of intra luminal vesicles. BMP also regulates cholesterol homeostasis and trafficking of lysosomal enzymes.

Packaging

5 mL Clear Glass Sealed Ampule (857133C-50mg)

5 mL Clear Glass Sealed Ampule (857133C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372
• Precautionary Statements: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Target Organs: Liver,Kidney, Respiratory system
• WGK: WGK 3