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840051C

Avanti

Egg PC

Avanti Research™ - A Croda Brand

Synonym(s):

Egg PC 99%

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About This Item

CAS Number:
97281-44-2
UNSPSC Code:
12352211
NACRES:
NA.25

description

L-α-phosphatidylcholine (Egg, Chicken), chloroform

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 2.5 mL (840051C-25mg)
pkg of 2 × 20 mL (840051C-1g)
pkg of 2 × 4 mL (840051C-200mg)
pkg of 5 × 4 mL (840051C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

10 mg/mL (840051C-25mg)
25 mg/mL (840051C-1g)
25 mg/mL (840051C-200mg)
25 mg/mL (840051C-500mg)

lipid type

phospholipids
phosphoglycerides

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1

InChI key

WTJKGGKOPKCXLL-VYOBOKEXSA-N

General description

L-α-phosphatidylcholine constitutes 20% of the total phospholipids in chicken egg. At sn-1 and sn-2 positions it has palmitic acid (16:0) and oleic acid (18:1), respectively.

Application

Egg PC has been used:
  • in the preparation of unilamellar vesicles
  • in liposome preparation for proteoliposome reconstitution
  • as a liposome component in lipid transfer assay

Biochem/physiol Actions

Egg PC (phosphatidylcholine) in its saturated form favors inhibition of cholesterol absorption. It also serves as a substrate for microbes for the synthesis of trimethylamine N-oxide (TMAO) thereby contributing to cardiovascular disease (CVD) risk. It is used in lipid preparation and liposomes for biophysical studies.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap; Argon Filled Foil Pouch (840051C-1g)
5 mL Clear Glass Sealed Ampule; Argon Filled Foil Pouch (840051C-200mg)
5 mL Clear Glass Sealed Ampule; Argon Filled Foil Pouch (840051C-25mg)
5 mL Clear Glass Sealed Ampule; Argon Filled Foil Pouch (840051C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Using optical trap to measure the refractive index of a single animal virus in culture fluid with high precision
Pang Y, et al.
Biomedical Optics Express, 7(5), 1672-1689 (2016)
Characterization of interactions of eggPC lipid structures with different biomolecules
Chahar FC, et al.
Chemistry and Physics of Lipids, 210(4), 60-69 (2018)
Christina M Bailey et al.
Langmuir : the ACS journal of surfaces and colloids, 33(43), 11986-11997 (2017-09-28)
Supported lipid bilayers (SLBs) have been used extensively in a variety of biotechnology applications and fundamental studies exploring lipid behavior. Despite their widespread use, various physicochemical parameters have yet to be thoroughly investigated for their impact on SLB formation. In
Msp1 is a membrane protein dislocase for tail-anchored proteins
Wohlever ML, et al.
Molecular Cell, 67(2), 194-202 (2017)
J Zebialowicz Ahlström et al.
Respiratory research, 20(1), 245-245 (2019-11-07)
In acute respiratory distress syndrome (ARDS) damaged alveolar epithelium, leakage of plasma proteins into the alveolar space and inactivation of pulmonary surfactant lead to respiratory dysfunction. Lung function could potentially be restored with exogenous surfactant therapy, but clinical trials have
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